Phenotypes associated with this allele

• Allele Symbol: Ncoa2^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6377204
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ncoa2^em1(IMPC)Mbp/Ncoa2^em1(IMPC)Mbp	C57BL/6N-Ncoa2^em1(IMPC)Mbp/MbpMmucd	MGI:6492972
ht2	Ncoa2^em1(IMPC)Mbp/Ncoa2^+	C57BL/6N-Ncoa2^em1(IMPC)Mbp/MbpMmucd	MGI:6492971

Genotype
MGI:6492972

hm1

• Allelic Composition: Ncoa2^em1(IMPC)Mbp/Ncoa2^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Ncoa2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Ncoa2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal umbilical cord morphology ( J:211773 )

IMPC - UCD

growth/size/body

abnormal body wall morphology ( J:211773 )

♀

IMPC - UCD

limbs/digits/tail

abnormal tail morphology ( J:211773 )

♀

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6492971

ht2

• Allelic Composition: Ncoa2^em1(IMPC)Mbp/Ncoa2⁺
• Genetic Background: C57BL/6N-Ncoa2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Ncoa2

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - UCD

decreased anxiety-related response ( J:211773 )

♂

IMPC - UCD

decreased thigmotaxis ( J:211773 )

♂

IMPC - UCD

decreased locomotor activity ( J:211773 )

♂

IMPC - UCD

hyperactivity ( J:211773 )

IMPC - UCD

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

enlarged spleen ( J:211773 )

♂

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating insulin level ( J:211773 )

♂

IMPC - UCD

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD