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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pignem1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6377205
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pignem1(IMPC)Mbp/Pignem1(IMPC)Mbp C57BL/6N-Pignem1(IMPC)Mbp/MbpMmucd MGI:7317039
ht2
 		Pignem1(IMPC)Mbp/Pign+ C57BL/6N-Pignem1(IMPC)Mbp/MbpMmucd MGI:6696855


Genotype
MGI:7317039
hm1
Allelic
Composition		 Pignem1(IMPC)Mbp/Pignem1(IMPC)Mbp
Genetic
Background		 C57BL/6N-Pignem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pignem1(IMPC)Mbp mutation (1 available); any Pign mutation (68 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

craniofacial
facial cleft ( J:211773 )
IMPC - UCD

embryo

growth/size/body
facial cleft ( J:211773 )
IMPC - UCD
abnormal head shape ( J:211773 )
IMPC - UCD
embryonic growth retardation ( J:211773 )
IMPC - UCD

homeostasis/metabolism
edema ( J:211773 )
IMPC - UCD

mortality/aging

nervous system
exencephaly ( J:211773 )
IMPC - UCD

vision/eye
anophthalmia ( J:211773 )
IMPC - UCD




Genotype
MGI:6696855
ht2
Allelic
Composition		 Pignem1(IMPC)Mbp/Pign+
Genetic
Background		 C57BL/6N-Pignem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pignem1(IMPC)Mbp mutation (1 available); any Pign mutation (68 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperactivity ( J:211773 )
IMPC - UCD

endocrine/exocrine glands
enlarged testis ( J:211773 )
IMPC - UCD

integument

liver/biliary system
small liver ( J:211773 )
IMPC - UCD

renal/urinary system
small kidney ( J:211773 )
IMPC - UCD

reproductive system
enlarged testis ( J:211773 )
IMPC - UCD

vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory