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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trim36tm1Htan
targeted mutation 1, Hiromitsu Tanaka
MGI:6378209
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trim36tm1Htan/Trim36tm1Htan involves: C57BL/6 MGI:6724062


Genotype
MGI:6724062
hm1
Allelic
Composition		 Trim36tm1Htan/Trim36tm1Htan
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trim36tm1Htan mutation (1 available); any Trim36 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased sperm progressive motility ( J:307617 )
• significantly lower total and progressive motility and reduced velocity
• no morphological abnomality was found in testes and sperm of homozyougs males
• the acrosome reaction under in vitro fertilization condition was also normal

reproductive system
decreased sperm progressive motility ( J:307617 )
• significantly lower total and progressive motility and reduced velocity
• no morphological abnomality was found in testes and sperm of homozyougs males
• the acrosome reaction under in vitro fertilization condition was also normal
male infertility ( J:307617 )
• homozygous males were fertile showing a normal fertility rate in vivo, but could not fertilize oocytes in vitro




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory