All Phenotypes Coro2b<tm1Cya> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Coro2b^tm1Cya
targeted mutation 1, Cyagen Biosciences
MGI:6379355

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Coro2b^tm1Cya/Coro2b^tm1Cya Tg(Nphs2-cre)1Seq/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:6379358

Allelic Composition	Coro2b^tm1Cya/Coro2b^tm1Cya Tg(Nphs2-cre)1Seq/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Coro2b^tm1Cya mutation (0 available); any Coro2b mutation (69 available)
Tg(Nphs2-cre)1Seq mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:279853 )

N	• mice do not show albuminuria or glomerular abnormalities • mice show a similar level of nephropathy as wild-type mice when treated with streptozotocin (STZ) to induce diabetes

decreased susceptibility to injury ( J:279853 )

• podocytes are partially protected against protamine sulfate-induced foot process effacement

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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