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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chaserrem1Wei
endonuclease-mediated mutation 1, Weizmann Institute of Science
MGI:6380711
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chaserrem1Wei/Chaserrem1Wei involves: BALB/c * C57BL/6 MGI:6384258
ht2
 		Chaserrem1Wei/Chaserr+ involves: BALB/c * C57BL/6 MGI:6384259
cx3
 		Chaserrem1Wei/Chaserr+
Chd2em1Wei/Chd2+ 		involves: BALB/c * C57BL/6 MGI:6384261
cx4
 		Chaserrem1Wei/Chaserrem1Wei
Chd2em1Wei/Chd2em1Wei 		involves: BALB/c * C57BL/6 MGI:6384262


Genotype
MGI:6384258
hm1
Allelic
Composition		 Chaserrem1Wei/Chaserrem1Wei
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserrem1Wei mutation (0 available); any Chaserr mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:281371 )
• no pups are recovered at weaning




Genotype
MGI:6384259
ht2
Allelic
Composition		 Chaserrem1Wei/Chaserr+
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserrem1Wei mutation (0 available); any Chaserr mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:281371 )
• mice die between E18.5 and weaning

reproductive system
abnormal female reproductive system physiology ( J:281371 )
• female mice rarely become pregnant

growth/size/body
malocclusion ( J:281371 )
decreased body weight ( J:281371 )
• in female and male mice
postnatal growth retardation ( J:281371 )

skeleton

adipose tissue

craniofacial




Genotype
MGI:6384261
cx3
Allelic
Composition		 Chaserrem1Wei/Chaserr+
Chd2em1Wei/Chd2+
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserrem1Wei mutation (0 available); any Chaserr mutation (11 available)
Chd2em1Wei mutation (0 available); any Chd2 mutation (190 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:281371 )
• fewer than expected mice are born

growth/size/body
decreased body weight ( J:281371 )




Genotype
MGI:6384262
cx4
Allelic
Composition		 Chaserrem1Wei/Chaserrem1Wei
Chd2em1Wei/Chd2em1Wei
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserrem1Wei mutation (0 available); any Chaserr mutation (11 available)
Chd2em1Wei mutation (0 available); any Chd2 mutation (190 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:281371 )
• mice are born in Mendelian ratios and exhibit no phenotype




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory