Phenotypes associated with this allele

• Allele Symbol: Tbx1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6382398
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbx1^em1(IMPC)Mbp/Tbx1^em1(IMPC)Mbp	C57BL/6NCrl-Tbx1^em1(IMPC)Mbp/MbpMmucd	MGI:7415107
ht2	Tbx1^em1(IMPC)Mbp/Tbx1^+	C57BL/6NCrl-Tbx1^em1(IMPC)Mbp/MbpMmucd	MGI:7415106

Genotype
MGI:7415107

hm1

• Allelic Composition: Tbx1^em1(IMPC)Mbp/Tbx1^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Tbx1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tbx1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

♂

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:7415106

ht2

• Allelic Composition: Tbx1^em1(IMPC)Mbp/Tbx1⁺
• Genetic Background: C57BL/6NCrl-Tbx1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tbx1

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

♀

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

abnormal pancreas morphology ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

♀

IMPC - UCD

anophthalmia ( J:211773 )

♂

IMPC - UCD