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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nudt12em1Rspi
endonuclease-mediated mutation 1, Ramesh S Pillai
MGI:6382616
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nudt12em1Rspi/Nudt12em1Rspi involves: C57BL/6J * DBA/2J MGI:6382649
ht2
 		Nudt12em1Rspi/Nudt12+ involves: C57BL/6J * DBA/2J MGI:6382650


Genotype
MGI:6382649
hm1
Allelic
Composition		 Nudt12em1Rspi/Nudt12em1Rspi
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nudt12em1Rspi mutation (0 available); any Nudt12 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal metabolism ( J:282288 )
• increased NADH levels, but not NAD levels, in the liver, kidney and testis
• circadian clock transcripts are increased




Genotype
MGI:6382650
ht2
Allelic
Composition		 Nudt12em1Rspi/Nudt12+
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nudt12em1Rspi mutation (0 available); any Nudt12 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal metabolism ( J:282288 )
• increased NADH levels, but not NAD levels, in the liver, kidney and testis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory