Phenotypes associated with this allele

• Allele Symbol: Slc18b1^tm1.1Ubc
• Allele Name: targeted mutation 1.1, Uppsala University
• Allele ID: MGI:6383711
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Slc18b1^tm1.1Ubc/Slc18b1^tm1.1Ubc Tg(Pgk1-cre)1Lni/0	involves: 129 * BALB/c * C57BL/6 * SJL	MGI:6383821

Genotype
MGI:6383821

cn1

• Allelic Composition: Slc18b1^tm1.1Ubc/Slc18b1^tm1.1Ubc; Tg(Pgk1-cre)1Lni/0
• Genetic Background: involves: 129 * BALB/c * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

enhanced behavioral response to amphetamine ( J:282689 )

• increased activity compared treated with wild-type mice

impaired behavioral response to addictive substance ( J:282689 )

• partial resistance to the effect of benzodiazepines based on lower reduction of locomotion compared with treated wild-type mice

abnormal operant conditioning behavior ( J:282689 )

• impaired behavior in a sucrose pellets self-administration paradigm

impaired long-term object recognition memory ( J:282689 )

• impaired memory function

impaired short-term object recognition memory ( J:282689 )

• impaired

abnormal spatial reference memory ( J:282689 )

• increased time to consume pellets in a radial arm maze

abnormal spatial working memory ( J:282689 )

• impaired

impaired learning ( J:282689 )

• in a radial arm maze test

homeostasis/metabolism

abnormal metabolism ( J:282689 )

• reduced brain polyamine content