Phenotypes associated with this allele

• Allele Symbol: Opa1^em1(IMPC)Bay
• Allele Name: endonuclease-mediated mutation 1, Baylor College of Medicine
• Allele ID: MGI:6384604
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Opa1^em1(IMPC)Bay/Opa1^em1(IMPC)Bay	C57BL/6N-Opa1^em1(IMPC)Bay/BayMmucd	MGI:6731392
ht2	Opa1^em1(IMPC)Bay/Opa1^+	C57BL/6N-Opa1^em1(IMPC)Bay/BayMmucd	MGI:7629069

Genotype
MGI:6731392

hm1

• Allelic Composition: Opa1^em1(IMPC)Bay/Opa1^em1(IMPC)Bay
• Genetic Background: C57BL/6N-Opa1^em1(IMPC)Bay/BayMmucd

Data Sources

IMPC Data for Opa1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - BCM

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal neural tube morphology ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

IMPC - BCM

abnormal somite shape ( J:211773 )

IMPC - BCM

abnormal visceral yolk sac morphology ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

IMPC - BCM

abnormal forebrain development ( J:211773 )

IMPC - BCM

Genotype
MGI:7629069

ht2

• Allelic Composition: Opa1^em1(IMPC)Bay/Opa1⁺
• Genetic Background: C57BL/6N-Opa1^em1(IMPC)Bay/BayMmucd

Data Sources

IMPC Data for Opa1

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - BCM