Analysis Tools
homeostasis/metabolism
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• mice exhibit normal serum levels alanine transaminase, bile, and non-esterified free fatty acids
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• mice fed a high-fructose diet exhibit reduced body weight and blood glucose levels compared with wild-type mice
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• increased blood and urine fructose level in mice fed a high-fructose diet
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• mice fed a high-fructose diet exhibit reduced body weight and blood glucose levels compared with wild-type mice
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• in mice fasted for either 6 h or overnight
• however, fed mice exhibit normal levels
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• in mice fed ad libitum
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• in fasted mice
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• modestly
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• moderately in fed mice
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• decreased hepatic glucose production determined by an intraperitoneal sodium pyruvate tolerance test
• mice fail to exhibit glucose production in response to a fructose load unlike wild-type
• reduced glycogen-stimulated glucose production in hepatocyte
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• in mice fed standard chow or a high-fructose diet
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• in fed, fasted or refed mice
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• in mice fed a high-fructose diet
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• in fasted mice
• in mice fed a high-fructose diet
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• increased blood and urine fructose level in mice fed a high-fructose diet
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• in mice fed a high-fructose diet
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liver/biliary system
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• in fed, fasted or refed mice
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• in fasted mice
• in mice fed a high-fructose diet
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• in mice fed standard chow or a high-fructose diet
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• mice fed a high-fructose diet exhibit increased intrahepatic ATP levels and decreased intrahepatic ADP levels compared with wild-type mice
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renal/urinary system
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• increased blood and urine fructose level in mice fed a high-fructose diet
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• in mice fed a high-fructose diet
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growth/size/body
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• mice fed a high-fructose diet exhibit reduced body weight and blood glucose levels compared with wild-type mice
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