Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(CAG-COX7A2L)#Sinos transgene insertion, Satoshi Inoue MGI:6384937 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• brown adipose tissue weight is increased more than in wild-type mice but less than in single Cox7a1lGt(OST241316)Lex homozygotes
|
| N |
• mice exhibit normal running ability in the forced treadmill test
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice show an increase in CO2 production (VCO2) in the steady state
|
|
• mice show an increase in oxygen consumption (VO2) in the steady state
|
|
• mice show 130% of the running capacity in the forced treadmill test
|
|
• cytochrome c oxidase (COX) activity is enhanced in MEFs
|
|
• cell proliferation is enhanced in MEFs
|
| N |
• brown adipose tissue weights are similar to wild-type mice
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
|
|
|
||
