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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gm30731tm1.1Dalm
targeted mutation 1.1, Daniel A Lim
MGI:6385064
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * C57BL/6NCrl MGI:6385158
cn2
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Emx1tm1(cre)Krj/Emx1+
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 MGI:6385155
cn3
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
involves: 129S/SvEv * C57BL/6 MGI:6385157


Genotype
MGI:6385158
cn1
Allelic
Composition
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gm30731tm1.1Dalm mutation (0 available); any Gm30731 mutation (0 available)
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze mutation (5 available); any Gt(ROSA)26Sor mutation (993 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• cell-autonomous increased neurogenesis following injection of a cre-expressing adenovirus into lateral ventricles at E13.5




Genotype
MGI:6385155
cn2
Allelic
Composition
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Emx1tm1(cre)Krj/Emx1+
Genetic
Background
involves: 129S/SvEv * 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1(cre)Krj mutation (2 available); any Emx1 mutation (34 available)
Gm30731tm1.1Dalm mutation (0 available); any Gm30731 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• altered postnatal cortical lamination
• of CTIP2+neurons in the cortical plate at E13.5
• reduced proliferation of ventricular zone cells at E13.5
• fewer neurons born at E15.5 and P14 in the cortex with reduced BrdU+;CUX1+ cells in the upper layers




Genotype
MGI:6385157
cn3
Allelic
Composition
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gm30731tm1.1Dalm mutation (0 available); any Gm30731 mutation (0 available)
Ndor1Tg(UBC-cre/ERT2)1Ejb mutation (6 available); any Ndor1 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• increased neurogenesis of ventricular-subventricular zone neural stem cell cultures treated with tamoxifen with 6-fold more neurons





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory