All Phenotypes Gm30731<tm1.2Dalm> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gm30731^tm1.2Dalm
targeted mutation 1.2, Daniel A Lim
MGI:6385065

Summary

2 genotypes

Allelic Composition	Gm30731^tm1.2Dalm/Gm30731^tm1.2Dalm
Genetic Background	involves: 129S/SvEv * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

thin cerebral cortex ( J:281278 )

• at E13.5

decreased neuron number ( J:281278 )

• reduced CTIP2+ cells at E13.5 in the cortical plate

• reduced proliferation

Allelic Composition	Gm30731^tm1.2Dalm/Gm30731^tm1.2Dalm Tg(Gm30731)#Dalm/0
Genetic Background	involves: 129S/SvEv * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:281278 )

N	• cortical thickness, neurogenesis and neuron proliferation are rescued by transgene expression

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