All Phenotypes Tph2<em1(IMPC)Mbp> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tph2^em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6386305

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tph2^em1(IMPC)Mbp/Tph2^em1(IMPC)Mbp	C57BL/6N-Tph2^em1(IMPC)Mbp/MbpMmucd	MGI:7267115
ht2	Tph2^em1(IMPC)Mbp/Tph2⁺	C57BL/6N-Tph2^em1(IMPC)Mbp/MbpMmucd	MGI:7267114

Allelic Composition	Tph2^em1(IMPC)Mbp/Tph2^em1(IMPC)Mbp
Genetic Background	C57BL/6N-Tph2^em1(IMPC)Mbp/MbpMmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tph2^em1(IMPC)Mbp mutation (1 available); any Tph2 mutation (43 available)

Data Sources

IMPC Data for Tph2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

IMPC - UCD

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

IMPC - UCD

enlarged ovary ( J:211773 )

IMPC - UCD

growth/size/body

enlarged ovary ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

increased eosinophil cell number ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

immune system

increased eosinophil cell number ( J:211773 )

IMPC - UCD

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

IMPC - UCD

enlarged ovary ( J:211773 )

IMPC - UCD

Allelic Composition	Tph2^em1(IMPC)Mbp/Tph2⁺
Genetic Background	C57BL/6N-Tph2^em1(IMPC)Mbp/MbpMmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tph2^em1(IMPC)Mbp mutation (1 available); any Tph2 mutation (43 available)

Data Sources

IMPC Data for Tph2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

IMPC - UCD

enlarged testis ( J:211773 )

IMPC - UCD

growth/size/body

enlarged kidney ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - UCD

small liver ( J:211773 )

IMPC - UCD

nervous system

abnormal brain morphology ( J:211773 )

IMPC - UCD

increased brain size ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

IMPC - UCD

reproductive system

abnormal testis morphology ( J:211773 )

IMPC - UCD

enlarged testis ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - UCD

abnormal retina vasculature morphology ( J:211773 )

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24