Phenotypes associated with this allele

• Allele Symbol: Tg(Rho-Pdcl*)#Msok
• Allele Name: transgene insertion, Maxim Sokolov
• Allele ID: MGI:6386387
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Rho-Pdcl*)#Msok/0	involves: 129	MGI:6386388

Genotype
MGI:6386388

tg1

• Allelic Composition: Tg(Rho-Pdcl*)#Msok/0
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal photoreceptor outer segment morphology ( J:283225 )

• photoreceptors show defects in outer segments or the ciliary compartments before weaning

• the outer segments do not separate from the photoreceptor cell body at P10

abnormal photoreceptor outer segment disc membrane morphology ( J:283225 )

• the outer segment discs are reduced in number and disarrayed, whereas their connecting cilia are normal

retina photoreceptor degeneration ( J:283225 )

• mice show loss of photoreceptor cells starting around P10 and degeneration progresses rapidly

retina outer nuclear layer degeneration ( J:283225 )

• outer nuclear layer degeneration by P12

abnormal electroretinogram waveform feature ( J:283225 )

• electroretinography shows that mice fail to respond to light stimulation of any intensity at P25

nervous system

abnormal photoreceptor outer segment morphology ( J:283225 )

• photoreceptors show defects in outer segments or the ciliary compartments before weaning

• the outer segments do not separate from the photoreceptor cell body at P10

abnormal photoreceptor outer segment disc membrane morphology ( J:283225 )

• the outer segment discs are reduced in number and disarrayed, whereas their connecting cilia are normal

retina photoreceptor degeneration ( J:283225 )

• mice show loss of photoreceptor cells starting around P10 and degeneration progresses rapidly