Phenotypes associated with this allele

• Allele Symbol: Xrcc5^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6388354
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Xrcc5^em1(IMPC)Ccpcz/Xrcc5^em1(IMPC)Ccpcz	C57BL/6NCrl-Xrcc5^em1(IMPC)Ccpcz/Ccpcz	MGI:7629146

Genotype
MGI:7629146

hm1

• Allelic Composition: Xrcc5^{em1(IMPC)Ccpcz}/Xrcc5^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Xrcc5^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Xrcc5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - CCP-IMG

decreased grip strength ( J:211773 )

♂

IMPC - CCP-IMG

increased grip strength ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♂

IMPC - CCP-IMG

hyperactivity ( J:211773 )

IMPC - CCP-IMG

cardiovascular system

aorta stenosis ( J:211773 )

IMPC - CCP-IMG

abnormal retina blood vessel morphology ( J:211773 )

IMPC - CCP-IMG

increased heart weight ( J:211773 )

IMPC - CCP-IMG

abnormal heart left ventricle morphology ( J:211773 )

♀

IMPC - CCP-IMG

decreased heart left ventricle size ( J:211773 )

IMPC - CCP-IMG

thin ventricular wall ( J:211773 )

IMPC - CCP-IMG

decreased cardiac output ( J:211773 )

IMPC - CCP-IMG

decreased cardiac stroke volume ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - CCP-IMG

abnormal zygomatic bone morphology ( J:211773 )

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

small thymus ( J:211773 )

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

increased heart weight ( J:211773 )

IMPC - CCP-IMG

decreased lean body mass ( J:211773 )

♂

IMPC - CCP-IMG

increased kidney weight ( J:211773 )

IMPC - CCP-IMG

increased liver weight ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

small thymus ( J:211773 )

IMPC - CCP-IMG

decreased hemoglobin content ( J:211773 )

IMPC - CCP-IMG

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - CCP-IMG

increased mean corpuscular volume ( J:211773 )

IMPC - CCP-IMG

increased red blood cell distribution width ( J:211773 )

IMPC - CCP-IMG

increased mean platelet volume ( J:211773 )

IMPC - CCP-IMG

decreased leukocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

small spleen ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating triglyceride level ( J:211773 )

♀

IMPC - CCP-IMG

increased circulating phosphate level ( J:211773 )

IMPC - CCP-IMG

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

small thymus ( J:211773 )

IMPC - CCP-IMG

decreased leukocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

small spleen ( J:211773 )

IMPC - CCP-IMG

limbs/digits/tail

short tibia ( J:211773 )

IMPC - CCP-IMG

liver/biliary system

increased liver weight ( J:211773 )

♂

IMPC - CCP-IMG

renal/urinary system

increased kidney weight ( J:211773 )

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

female infertility ( J:211773 )

♀

IMPC - CCP-IMG

male infertility ( J:211773 )

♂

IMPC - CCP-IMG

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - CCP-IMG

abnormal zygomatic bone morphology ( J:211773 )

IMPC - CCP-IMG

short tibia ( J:211773 )

IMPC - CCP-IMG

abnormal spine curvature ( J:211773 )

IMPC - CCP-IMG

kyphosis ( J:211773 )

IMPC - CCP-IMG

scoliosis ( J:211773 )

♂

IMPC - CCP-IMG

abnormal vertebrae morphology ( J:211773 )

IMPC - CCP-IMG

abnormal vertebral arch morphology ( J:211773 )

IMPC - CCP-IMG

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal retina blood vessel morphology ( J:211773 )

IMPC - CCP-IMG