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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rcc1lm1Dgr
mutation 1, Daniel S Greenspan
MGI:6392239
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rcc1lm1Dgr/Rcc1lm1Dgr involves: 129X1/SvJ * Black Swiss * C57BL/6 MGI:6392244
cx2
 		Pcolcetm1Dgr/Pcolcetm1Dgr
Rcc1lm1Dgr/Rcc1lm1Dgr 		involves: 129X1/SvJ * Black Swiss * C57BL/6 MGI:6392243


Genotype
MGI:6392244
hm1
Allelic
Composition		 Rcc1lm1Dgr/Rcc1lm1Dgr
Genetic
Background		 involves: 129X1/SvJ * Black Swiss * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rcc1lm1Dgr mutation (0 available); any Rcc1l mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality prior to organogenesis ( J:254859 )
• mice exhibit early embryonic lethality




Genotype
MGI:6392243
cx2
Allelic
Composition		 Pcolcetm1Dgr/Pcolcetm1Dgr
Rcc1lm1Dgr/Rcc1lm1Dgr
Genetic
Background		 involves: 129X1/SvJ * Black Swiss * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcolcetm1Dgr mutation (0 available); any Pcolce mutation (70 available)
Rcc1lm1Dgr mutation (0 available); any Rcc1l mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
abnormal trophectoderm morphology ( J:254859 )
• fibrin clotting in the trophoblast component of chorio-vitelline placenta at E7.5
decreased trophoblast giant cell number ( J:254859 )
• small and abnormal with small nuclei




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory