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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dexiem1Kslr
endonuclease-mediated mutation 1, Stephan Kissler
MGI:6393839
Summary 2 genotypes


Genotype
MGI:6393944
hm1
Allelic
Composition		 Dexiem1Kslr/Dexiem1Kslr
Genetic
Background		 NOD/ShiLtJ-Dexiem1Kslr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dexiem1Kslr mutation (0 available); any Dexi mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system




Genotype
MGI:6393952
cx2
Allelic
Composition		 Dexiem1Kslr/Dexiem1Kslr
Tg(CMV-GFP,-RNAi:Clec16a)KD3Kslr/0
Genetic
Background		 NOD-Dexiem1Kslr Tg(CMV-GFP,-RNAi:Clec16a)KD3Kslr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dexiem1Kslr mutation (0 available); any Dexi mutation (9 available)
Tg(CMV-GFP,-RNAi:Clec16a)KD3Kslr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased physiological sensitivity to xenobiotic ( J:285312 )
• mice are protected from cyclophosphamide-induced diabetes as in Tg(CMV-GFP,-RNAi:Clec16a)KD3Kslr mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory