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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hmbstm2.1Rjde
targeted mutation 2.1, Robert J Desnick
MGI:6393999
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hmbstm2.1Rjde/Hmbstm2.1Rjde involves: 129/Sv * C57BL/6 MGI:6394001
ht2
 		Hmbstm1.1Rjde/Hmbstm2.1Rjde involves: 129/Sv * C57BL/6 MGI:6394010


Genotype
MGI:6394001
hm1
Allelic
Composition		 Hmbstm2.1Rjde/Hmbstm2.1Rjde
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmbstm2.1Rjde mutation (0 available); any Hmbs mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:275245 )
• embryonic lethal, however time of lethality is not specified




Genotype
MGI:6394010
ht2
Allelic
Composition		 Hmbstm1.1Rjde/Hmbstm2.1Rjde
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmbstm1.1Rjde mutation (0 available); any Hmbs mutation (25 available)
Hmbstm2.1Rjde mutation (0 available); any Hmbs mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:275245 )
• all die by P30

growth/size/body
decreased body size ( J:275245 )
• mice are severely runted
cachexia ( J:275245 )




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory