Phenotypes associated with this allele

• Allele Symbol: Rbm45^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:6400536
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rbm45^em1(IMPC)J/Rbm45^em1(IMPC)J	C57BL/6NJ-Rbm45^em1(IMPC)J/Mmjax	MGI:6731425
ht2	Rbm45^em1(IMPC)J/Rbm45^+	C57BL/6NJ-Rbm45^em1(IMPC)J/Mmjax	MGI:7267075

Genotype
MGI:6731425

hm1

• Allelic Composition: Rbm45^em1(IMPC)J/Rbm45^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Rbm45^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Rbm45

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - JAX

craniofacial

abnormal facial morphology ( J:211773 )

♀

IMPC - JAX

abnormal head shape ( J:211773 )

IMPC - JAX

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

♀

IMPC - JAX

abnormal head shape ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal body wall morphology ( J:211773 )

IMPC - JAX

homeostasis/metabolism

edema ( J:211773 )

IMPC - JAX

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - JAX

abnormal tail morphology ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

vision/eye

anophthalmia ( J:211773 )

IMPC - JAX

Genotype
MGI:7267075

ht2

• Allelic Composition: Rbm45^em1(IMPC)J/Rbm45⁺
• Genetic Background: C57BL/6NJ-Rbm45^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Rbm45

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - JAX

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - JAX

skeleton

decreased bone mineral density ( J:211773 )

♂

IMPC - JAX