Phenotypes associated with this allele

• Allele Symbol: Tsen54^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6402621
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tsen54^tm1b(EUCOMM)Wtsi/Tsen54^tm1b(EUCOMM)Wtsi	B6N(Cg)-Tsen54^tm1b(EUCOMM)Wtsi	MGI:6402776

Genotype
MGI:6402776

hm1

• Allelic Composition: Tsen54^{tm1b(EUCOMM)Wtsi}/Tsen54^{tm1b(EUCOMM)Wtsi}
• Genetic Background: B6N(Cg)-Tsen54^{tm1b(EUCOMM)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:261024 )

• no pups born and no embryos recovered at age E8.5

• 25% of embryos malformed or delayed starting from age E6.5 till E8.5

• normal Mendelian ratio at age E3.5

• normal development of extra-embryonic tissues at age E6.5 till E8.5