Phenotypes associated with this allele

• Allele Symbol: Rnf43^em1Mage
• Allele Name: endonuclease-mediated mutation 1, Markus Gerhard
• Allele ID: MGI:6403353
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf43^em1Mage/Rnf43^em1Mage	Not Specified	MGI:6403437

Genotype
MGI:6403437

hm1

• Allelic Composition: Rnf43^em1Mage/Rnf43^em1Mage
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

digestive/alimentary phenotype ( J:276360 )

N • normal intestinal and colon epithelium morphology and cell proliferation at age 12, 24 and 40 weeks

abnormal stomach glandular region morphology ( J:276360 )

• proliferation into lumen and thicker mucosa at age 24 and 40 weeks

• multifocal hyperplasia at age 16 weeks

abnormal stomach wall morphology ( J:276360 )

• proliferation into lumen and thicker mucosa at age 24 and 40 weeks

• multifocal hyperplasia at age 16 weeks

abnormal stomach mucosa morphology ( J:276360 )

• thicker mucosa at age 24 and 40 weeks

immune system

immune system phenotype ( J:276360 )

N • no inflammation of stomach

mortality/aging

mortality/aging ( J:276360 )

N • viable and born at expected Mendelian ratio