Phenotypes associated with this allele

• Allele Symbol: Ptpn18^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:6403887
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptpn18^em1(IMPC)J/Ptpn18^em1(IMPC)J	C57BL/6NJ-Ptpn18^em1(IMPC)J/Mmjax	MGI:6696872
ht2	Ptpn18^em1(IMPC)J/Ptpn18^+	C57BL/6NJ-Ptpn18^em1(IMPC)J/Mmjax	MGI:7317052

Genotype
MGI:6696872

hm1

• Allelic Composition: Ptpn18^em1(IMPC)J/Ptpn18^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Ptpn18^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Ptpn18

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased heart rate ( J:211773 )

♂

IMPC - JAX

prolonged RR interval ( J:211773 )

♂

IMPC - JAX

hematopoietic system

increased leukocyte cell number ( J:211773 )

♂

IMPC - JAX

immune system

increased leukocyte cell number ( J:211773 )

♂

IMPC - JAX

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:7317052

ht2

• Allelic Composition: Ptpn18^em1(IMPC)J/Ptpn18⁺
• Genetic Background: C57BL/6NJ-Ptpn18^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Ptpn18

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

IMPC - JAX

vision/eye

abnormal placement of pupils ( J:211773 )

♂

IMPC - JAX

cataract ( J:211773 )

♂

IMPC - JAX

persistence of hyaloid vascular system ( J:211773 )

IMPC - JAX