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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fkrptm1.2Pg
targeted mutation 1.2, PolyGene AG
MGI:6404019
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fkrptm1.2Pg/Fkrptm1.2Pg involves: 129P2/OlaHsd * FVB/N MGI:6404029
ht2
 		Fkrptm1.1Pg/Fkrptm1.2Pg involves: 129P2/OlaHsd * FVB/N MGI:6404028


Genotype
MGI:6404029
hm1
Allelic
Composition		 Fkrptm1.2Pg/Fkrptm1.2Pg
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkrptm1.2Pg mutation (0 available); any Fkrp mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6404028
ht2
Allelic
Composition		 Fkrptm1.1Pg/Fkrptm1.2Pg
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkrptm1.1Pg mutation (0 available); any Fkrp mutation (21 available)
Fkrptm1.2Pg mutation (0 available); any Fkrp mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal skeletal muscle fiber morphology ( J:285924 )
• tibialis anterior and quadriceps show increased internally nucleated fibers, with EDLs showing a greater increase
• EDLs show a 1.6% increase in the number of internally nucleated fibers at 5 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory