All Phenotypes Ace2<em1Shyy> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ace2^em1Shyy
endonuclease-mediated mutation 1, John Y J Shyy
MGI:6406963

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ace2^em1Shyy/Ace2^em1Shyy	B6.Cg-Ace2^em1Shyy	MGI:6449115

Allelic Composition	Ace2^em1Shyy/Ace2^em1Shyy
Genetic Background	B6.Cg-Ace2^em1Shyy

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ace2^em1Shyy mutation (0 available); any Ace2 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

pulmonary hypertension ( J:286356 )

• mice subjected to SU5416/hypoxia-reoxygenation show aggravated pulmonary hypertension compared to controls, characterized by elevated right ventricular systolic pressure, increased Fulton index, vascular blushing of small pulmonary arteries, and aggravated vasculature

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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