All Phenotypes Ace2<em2Shyy> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ace2^em2Shyy
endonuclease-mediated mutation 2, John Y J Shyy
MGI:6406965

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ace2^em2Shyy/Ace2^em2Shyy	B6.Cg-Ace2^em2Shyy	MGI:6449117

Allelic Composition	Ace2^em2Shyy/Ace2^em2Shyy
Genetic Background	B6.Cg-Ace2^em2Shyy

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ace2^em2Shyy mutation (0 available); any Ace2 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased pulmonary artery pressure ( J:286356 )

• mice subjected to SU5416/hypoxia-reoxygenation show reduced right ventricular systolic pressure and the Fulton index, largely abrogated pulmonary artery muscularization and luminal narrowing and preserved vascular integrity indicating resistance to pulmonary hypertension compared to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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