About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		nob10
no b wave 10
MGI:6423083
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		nob10/nob10 B6.Cg-nob10/Boc MGI:6423094


Genotype
MGI:6423094
hm1
Allelic
Composition		 nob10/nob10
Genetic
Background		 B6.Cg-nob10/Boc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
nob10 mutation (1 available); any nob10 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
retina photoreceptor degeneration ( J:287579 )
• histology and OCT show a thin retina with 20-30% photoreceptor loss, slow progressive loss after that

vision/eye
retina photoreceptor degeneration ( J:287579 )
• histology and OCT show a thin retina with 20-30% photoreceptor loss, slow progressive loss after that
retina spots ( J:287579 )
• evident by 6 months of age
abnormal electroretinogram waveform feature ( J:287579 )
• ERG at 3 weeks of age shows no b wave rod-mediated photoresponse and abnormal cone-mediated response




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory