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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Meiobtm1.1Jw
targeted mutation 1.1, Jeremy Wang
MGI:6423285
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Meiobtm1.1Jw/Meiobtm1.1Jw involves: 129S4/SvJae * C57BL/6 MGI:6456832


Genotype
MGI:6456832
hm1
Allelic
Composition		 Meiobtm1.1Jw/Meiobtm1.1Jw
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Meiobtm1.1Jw mutation (0 available); any Meiob mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal double-strand DNA break repair ( J:292036 )
• reduced intensity of BRME1 and HSF2BP punctuate foci in spermatocytes
• absent SPATA22 punctuate foci in spermatocytes

homeostasis/metabolism
abnormal double-strand DNA break repair ( J:292036 )
• reduced intensity of BRME1 and HSF2BP punctuate foci in spermatocytes
• absent SPATA22 punctuate foci in spermatocytes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory