Phenotypes associated with this allele

• Allele Symbol: Rnf168^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6433991
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf168^tm2b(EUCOMM)Hmgu/Rnf168^tm2b(EUCOMM)Hmgu	C57BL/6N-Rnf168^tm2b(EUCOMM)Hmgu/Ccpcz	MGI:6696882

Genotype
MGI:6696882

hm1

• Allelic Composition: Rnf168^{tm2b(EUCOMM)Hmgu}/Rnf168^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Rnf168^{tm2b(EUCOMM)Hmgu}/Ccpcz
• Cell Lines: HEPD0798_7_B10

Data Sources

IMPC Data for Rnf168

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

IMPC - CCP-IMG

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

decreased body weight ( J:211773 )

IMPC - CCP-IMG

abnormal head morphology ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

increased eosinophil cell number ( J:211773 )

♀

IMPC - CCP-IMG

decreased erythrocyte cell number ( J:211773 )

♀

IMPC - CCP-IMG

decreased hematocrit ( J:211773 )

♀

IMPC - CCP-IMG

decreased hemoglobin content ( J:211773 )

♀

IMPC - CCP-IMG

increased mean platelet volume ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

IMPC - CCP-IMG

increased circulating alanine transaminase level ( J:211773 )

IMPC - CCP-IMG

increased circulating aspartate transaminase level ( J:211773 )

IMPC - CCP-IMG

increased circulating creatine kinase level ( J:211773 )

IMPC - CCP-IMG

increased circulating lactate dehydrogenase level ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

increased eosinophil cell number ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - CCP-IMG

abnormal spine curvature ( J:211773 )

IMPC - CCP-IMG

vertebral fusion ( J:211773 )

♂

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - CCP-IMG

abnormal cornea morphology ( J:211773 )

IMPC - CCP-IMG

fused cornea and lens ( J:211773 )

♂

IMPC - CCP-IMG

microphthalmia ( J:211773 )

IMPC - CCP-IMG

anophthalmia ( J:211773 )

IMPC - CCP-IMG