mortality/aging
• homozygous mutant embryos die at an intermediate stage of embryonic development; no embryos are found around E15.5 to E16.5
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growth/size/body
• embryos exhibit severe embryonic growth retardation
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• embryos found at E10.5 are extremely small
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embryo
• embryos exhibit severe embryonic growth retardation
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• embryos found at E10.5 are extremely small
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