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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rbm20em3Hide
endonuclease-mediated mutation 3, Hidehito Kuroyanagi
MGI:6437214
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rbm20em3Hide/Rbm20em3Hide involves: C57BL/6J MGI:6477031


Genotype
MGI:6477031
hm1
Allelic
Composition		 Rbm20em3Hide/Rbm20em3Hide
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rbm20em3Hide mutation (0 available); any Rbm20 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased cardiac muscle contractility ( J:297234 )
• ultrasound echocardiography shows a slight but significant lower fractional shortening at 12-16 weeks of age
abnormal heart echocardiography feature ( J:297234 )
• ultrasound echocardiography shows a slight but significant lower fractional shortening at 12-16 weeks of age
atrial fibrillation ( J:297234 )
• 5% of mice develop atrial fibrillation at 16 weeks of age
prolonged QT interval ( J:297234 )
• prolonged heart rate-corrected QT interval in 4-week old mice

muscle
decreased cardiac muscle contractility ( J:297234 )
• ultrasound echocardiography shows a slight but significant lower fractional shortening at 12-16 weeks of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory