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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tesminem1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:6437394
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tesminem1Osb/Tesminem1Osb involves: C57BL/6NJcl * DBA/2NJcl MGI:6437396


Genotype
MGI:6437396
hm1
Allelic
Composition		 Tesminem1Osb/Tesminem1Osb
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tesminem1Osb mutation (4 available); any Tesmin mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
small testis ( J:288964 )
• testes remain smaller throughout life
decreased testis weight ( J:288964 )
• testicular weight is decreased in P14 mice but not P10 mice
arrest of spermatogenesis ( J:288964 )
• spermatogenesis is predominately arrested at an early stage before the appearance of haploid spermatogenic cells
arrest of male meiosis ( J:288964 )
• meiosis is arrested before late-pachytene stage

endocrine/exocrine glands
small testis ( J:288964 )
• testes remain smaller throughout life
decreased testis weight ( J:288964 )
• testicular weight is decreased in P14 mice but not P10 mice

cellular
arrest of male meiosis ( J:288964 )
• meiosis is arrested before late-pachytene stage




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory