Analysis Tools
reproductive system
 N |
• no abnormalities in ovarian follicle development are seen, hormone-primed females ovulate normal numbers of oocytes, zona pellucida structure appears normal
• in vitro fertilization with wild-type spermatozoa shows that mutant oocytes can be fertilized and the number of spermatozoa bound to mutant oocytes is similar to that in controls
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• females show a decrease in viable embryos between the morula stage and the blastocyst stage, resulting in reduced litter size
• however, females are fertile
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