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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rabl3xm
xiamen
MGI:6441472
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rabl3xm/Rabl3xm C57BL/6J-Rabl3xm MGI:6441540
ht2
Rabl3xm/Rabl3em1Btlr C57BL/6J-Rabl3xm Rabl3em1Btlr MGI:6441542


Genotype
MGI:6441540
hm1
Allelic
Composition
Rabl3xm/Rabl3xm
Genetic
Background
C57BL/6J-Rabl3xm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rabl3xm mutation (0 available); any Rabl3 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• increased CD44 expression in CD8+ T cells
• increased CD4+ to CD8+ T cell ratio
• reduced CD3+ T cell frequencies
• increased B cell to T cell ratio

immune system
• increased CD44 expression in CD8+ T cells
• increased CD4+ to CD8+ T cell ratio
• reduced CD3+ T cell frequencies
• increased B cell to T cell ratio




Genotype
MGI:6441542
ht2
Allelic
Composition
Rabl3xm/Rabl3em1Btlr
Genetic
Background
C57BL/6J-Rabl3xm Rabl3em1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rabl3em1Btlr mutation (0 available); any Rabl3 mutation (18 available)
Rabl3xm mutation (0 available); any Rabl3 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands

growth/size/body
• 30% smaller than WT littermates

hematopoietic system
N
• normal numbers of monocytes, platelets and neutrophils

immune system

mortality/aging
• slightly lower than expected Mendelian ratio





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory