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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rabl3em1Btlr
endonuclease-mediated mutation 1, Bruce Beutler
MGI:6441477
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rabl3em1Btlr/Rabl3em1Btlr C57BL/6J-Rabl3em1Btlr MGI:6441544
ht2
 		Rabl3xm/Rabl3em1Btlr C57BL/6J-Rabl3xm Rabl3em1Btlr MGI:6441542


Genotype
MGI:6441544
hm1
Allelic
Composition		 Rabl3em1Btlr/Rabl3em1Btlr
Genetic
Background		 C57BL/6J-Rabl3em1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rabl3em1Btlr mutation (0 available); any Rabl3 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6441542
ht2
Allelic
Composition		 Rabl3xm/Rabl3em1Btlr
Genetic
Background		 C57BL/6J-Rabl3xm Rabl3em1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rabl3em1Btlr mutation (0 available); any Rabl3 mutation (18 available)
Rabl3xm mutation (0 available); any Rabl3 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands

growth/size/body
decreased birth body size ( J:287198 )
• 30% smaller than WT littermates

hematopoietic system
hematopoietic system phenotype ( J:287198 )
N
• normal numbers of monocytes, platelets and neutrophils

immune system

mortality/aging
prenatal lethality, incomplete penetrance ( J:287198 )
• slightly lower than expected Mendelian ratio




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory