behavior/neurological
• total immobility time in the forced swim test is increased in males and females
• total immobility time in the tail suspension test is increased in males
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• males, but not females, show an increase in hindquarter fall
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• males, but not females, show a decrease in auricular reflex
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• mice show a reduction in surface righting reflex
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• females show diminished response when the tip of the tail is squeezed by forceps
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• abnormal movement of hindlimbs when held by the tail
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• mice take longer to cross the balance beam
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• males show shorter hindlimb step lengths
• males show greater forelimb spatial gait symmetry
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• males show shorter stride lengths for right and left fore- and hind-limbs
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• mice show increased distance traveled and speed in the open field
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