About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nfe2tm1.1Hlpa
targeted mutation 1.1, Heike Luise Pahl
MGI:6446746
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Nfe2tm1.1Hlpa/? involves: 129 * C57BL/6 MGI:6446751


Genotype
MGI:6446751
ot1
Allelic
Composition		 Nfe2tm1.1Hlpa/?
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfe2tm1.1Hlpa mutation (0 available); any Nfe2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased acute myeloid leukemia incidence ( J:275444 )
• acute myeloid leukemia sometimes accompanies the development of granulocytic sarcoma
increased myeloid sarcoma incidence ( J:275444 )
• 23% of mice develop a granulocytic sarcoma with or without an accompanying acute myeloid leukemia (AML)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory