Phenotypes associated with this allele

• Allele Symbol: Btbd3^em1Dul
• Allele Name: endonuclease-mediated mutation 1, Stephanie C Dulawa
• Allele ID: MGI:6446945
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Btbd3^em1Dul/Btbd3^em1Dul	C57BL/6-Btbd3^em1Dul	MGI:6446966

Genotype
MGI:6446966

cn1

• Allelic Composition: Btbd3^em1Dul/Btbd3^em1Dul
• Genetic Background: C57BL/6-Btbd3^em1Dul

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal habituation to a new environment ( J:291459 )

• reduced locomotor habituation in open field test

decreased exploration in new environment ( J:291459 )

abnormal anxiety-related response ( J:291459 )

• reduced marble burying

increased thigmotaxis ( J:291459 )

• more time spent at perimeters (reduced spatial d) in open field test

decreased vertical activity ( J:291459 )

• reduced instances of rearing in first 5 minutes in open field test

increased locomotor activity ( J:291459 )

• more time spent at perimeters (reduced spatial d) in open field test

• increased locomotor activity in open field test

• normal wheel-running activity

abnormal nest building behavior ( J:291459 )

• reduced use of nestlet material, also when gene knocked-down in dorsal hippocampus only