All Phenotypes Clstn3<tm1c(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Clstn3^{tm1c(EUCOMM)Hmgu}
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:6449227

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Lyz2^tm1(cre)Ifo/Lyz2⁺	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL	MGI:6454084
cn2	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(Syn1-cre)671Jxm/0	involves: C57BL/6 * C57BL/6N * CBA * SJL	MGI:6454088
cn3	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(BGLAP-cre)1Clem/0	involves: C57BL/6 * C57BL/6N * FVB/NJ * SJL	MGI:6454085
cn4	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(Dbh-cre)KH212Gsat/0	involves: C57BL/6 * C57BL/6N * FVB/NTac * SJL	MGI:6454087

Allelic Composition	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clstn3^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Clstn3 mutation (66 available)
Lyz2^tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:293885 )

N	• normal bone morphology

Allelic Composition	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(Syn1-cre)671Jxm/0
Genetic Background	involves: C57BL/6 * C57BL/6N * CBA * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clstn3^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Clstn3 mutation (66 available)
Tg(Syn1-cre)671Jxm mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

decreased bone marrow adipose tissue amount ( J:293885 )

• reduced bone marrow volume

growth/size/body

decreased body mass index ( J:293885 )

• from age 6 weeks on normal chow

limbs/digits/tail

limbs/digits/tail phenotype ( J:293885 )

N	• normal volume fraction, thickness, number, and separation of trabecular bone in distal metaphysis

skeleton

decreased bone marrow adipose tissue amount ( J:293885 )

• reduced bone marrow volume

decreased compact bone mass ( J:293885 )

• at distal metaphysis and midshaft regions of femur

• normal cortical bone thickness

Allelic Composition	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(BGLAP-cre)1Clem/0
Genetic Background	involves: C57BL/6 * C57BL/6N * FVB/NJ * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clstn3^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Clstn3 mutation (66 available)
Tg(BGLAP-cre)1Clem mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:293885 )

N	• normal bone morphology

Allelic Composition	Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(Dbh-cre)KH212Gsat/0
Genetic Background	involves: C57BL/6 * C57BL/6N * FVB/NTac * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clstn3^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Clstn3 mutation (66 available)
Tg(Dbh-cre)KH212Gsat mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

growth/size/body region phenotype ( J:293885 )

N	• normal body weight

limbs/digits/tail

limbs/digits/tail phenotype ( J:293885 )

N	• normal bone morphology

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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