Phenotypes associated with this allele

• Allele Symbol: Rnf220^em1Kust
• Allele Name: endonuclease-mediated mutation 1, Kunming University of Science and Technnology
• Allele ID: MGI:6451111
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tg(Ddx4-cre)1Dcas/0 Rnf220^em1Kust/Rnf220^em1Kust	involves: C57BL/6 * FVB	MGI:6451400

Genotype
MGI:6451400

cn1

• Allelic Composition: Tg(Ddx4-cre)1Dcas/0; Rnf220^em1Kust/Rnf220^em1Kust
• Genetic Background: involves: C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:291960 )

♀

embryo

abnormal neural tube morphology ( J:291960 )

♀ • at E10.5, mice exhibit a ventral expansion of intermediate V0, dorsal expansion of ventral V3 neurons, and reduced V1, V2, and motor neurons between them compared with control mice

skeleton

skeleton phenotype ( J:291960 )

♀ • mice exhibit normal skeleton pattern and morphology

nervous system

abnormal neural tube morphology ( J:291960 )

♀ • at E10.5, mice exhibit a ventral expansion of intermediate V0, dorsal expansion of ventral V3 neurons, and reduced V1, V2, and motor neurons between them compared with control mice

decreased motor neuron number ( J:291960 )

♀ • in the dorsal neural tube at E10.5