All Phenotypes Fau<tm1.1Smoc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fau^tm1.1Smoc
targeted mutation 1.1, Shanghai Model Organisms Center
MGI:6452962

Summary

2 genotypes

Allelic Composition	Fau^tm1.1Smoc/Fau^tm1.1Smoc
Genetic Background	involves: 129 * C57BL/6J * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fau^tm1.1Smoc mutation (0 available); any Fau mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no mice are produced from breeding heterozygotes

Allelic Composition	Fau^tm1.1Smoc/Fau⁺
Genetic Background	involves: 129 * C57BL/6J * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fau^tm1.1Smoc mutation (0 available); any Fau mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal endometrium morphology ( J:293342 )

• abnormal endometrial stromal cells do not support blastocyst hatching, invading, and spreading as well as wild-type cells

decreased litter size ( J:293342 )

• female mice produce smaller litters than wild-type mice

cellular

maternal effect ( J:293342 )

• female mice produce exhibit fewer and abnormal fetuses at E11 regardless of embryo phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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