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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prss55em1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:6454671
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prss55em1Osb/Prss55em1Osb involves: C57BL/6NJcl * DBA/2NJcl MGI:6454994


Genotype
MGI:6454994
hm1
Allelic
Composition		 Prss55em1Osb/Prss55em1Osb
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prss55em1Osb mutation (2 available); any Prss55 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reduced male fertility ( J:293896 )
• male mice produce fewer offspring compared with wild-type mice
decreased fertilization frequency ( J:293896 )
• spermatozoa exhibit decreased fertilization of cumulus-free oocytes compared with wild-type spermatozoa
• however, fertilization of cumulus-intact and zona pellucida-free oocytes is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory