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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prr19em2Atot
endonuclease-mediated mutation 2, Attila Toth
MGI:6455145
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prr19em2Atot/Prr19em2Atot either: (involves: C57BL/6JCrl) or (involves: CD-1) MGI:6455165


Genotype
MGI:6455165
hm1
Allelic
Composition		 Prr19em2Atot/Prr19em2Atot
Genetic
Background		 either: (involves: C57BL/6JCrl) or (involves: CD-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prr19em2Atot mutation (0 available); any Prr19 mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal meiosis ( J:292293 )
• mice fail in crossover differentiation unlike wild-type mice

homeostasis/metabolism
abnormal double-strand DNA break repair ( J:292293 )
• delayed repair in spermatocytes and oocytes

cellular
abnormal meiosis ( J:292293 )
• mice fail in crossover differentiation unlike wild-type mice
abnormal double-strand DNA break repair ( J:292293 )
• delayed repair in spermatocytes and oocytes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory