Phenotypes associated with this allele

• Allele Symbol: Rnase1^tm1.2Rtrs
• Allele Name: targeted mutation 1.2, Ronald T Raines
• Allele ID: MGI:6456551
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnase1^tm1.2Rtrs/Rnase1^tm1.2Rtrs	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6	MGI:6456561

Genotype
MGI:6456561

hm1

• Allelic Composition: Rnase1^tm1.2Rtrs/Rnase1^tm1.2Rtrs
• Genetic Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal blood homeostasis ( J:288762 )

• increased plasma RNA levels

abnormal blood coagulation ( J:288762 )

• quicker plasma clotting after recalcification

• however, coagulation with actin FSL activated partial thromboplastin time reagent is normal and mice exhibit normal coagulation in vivo

abnormal enzyme/coenzyme activity ( J:288762 )

• elevated FXII and FXI activity plasma levels with to without an activator

growth/size/body

increased body weight ( J:288762 )

• in male and female mice