Phenotypes associated with this allele

• Allele Symbol: Serinc5^em1Spst
• Allele Name: endonuclease-mediated mutation 1, Spyridon Stavrou
• Allele ID: MGI:6456568
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Serinc5^em1Spst/Serinc5^em1Spst	C57BL/6-Serinc5^em1Spst	MGI:6456578

Genotype
MGI:6456578

hm1

• Allelic Composition: Serinc5^em1Spst/Serinc5^em1Spst
• Genetic Background: C57BL/6-Serinc5^em1Spst

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:291232 )

N • mice exhibit normal levels of dendritic cells, B cells, T cells and macrophages

N • mice infected with wild-type ecotropic Friend murine leukemia virus (F-MLV) or mutated F-MLV exhibit similar virus titers in the spleen at 10 days post infection (dpi) as infected wild-type mice

N • mice infected with an MLV virus with a mutated glycosylated Gag protein and containing the amphotropic MLV 4070A envelope instead of the ecotropic envelope (gGag^mutF-MLV/Ampho^Env) show higher virus titers than infected wild-type mice