Phenotypes associated with this allele

• Allele Symbol: Garem2^tm1.2Hkon
• Allele Name: targeted mutation 1.2, Hiroaki Konishi
• Allele ID: MGI:6456657
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Garem2^tm1.2Hkon/Garem2^tm1.2Hkon	involves: C57BL * C57BL/6JJcl * DBA	MGI:6456659

Genotype
MGI:6456659

hm1

• Allelic Composition: Garem2^tm1.2Hkon/Garem2^tm1.2Hkon
• Genetic Background: involves: C57BL * C57BL/6JJcl * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased exploration in new environment ( J:287781 )

increased coping response ( J:287781 )

• in a tail suspension test, mice exhibit longer latency to immobile behavior compared with wild-type mice

decreased anxiety-related response ( J:287781 )

• in an elevated plus maze and an open field

• however, anxiety response in a light/dark transition test is normal

increased vertical activity ( J:287781 )

• in an open field

abnormal social/conspecific interaction behavior ( J:287781 )

• mildly high social approaching behavior

nervous system

abnormal neurite morphology ( J:287781 )

• shorter neurite lengths in primary cultures