homeostasis/metabolism
• in islets from mice fed standard chow or a high-fat diet after glucose stimulation or treatment with 35 mM KCl
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• mice fed a high-fat diet exhibit reduced serum insulin concentrations compared with control mice
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• after glucose injection or fed a high-fat diet
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• in mice challenged with IPGTT or fed a high-fat diet
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endocrine/exocrine glands
• increased beta-cell differentiation as determined by marker expression
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• in islets from mice fed standard chow or a high-fat diet after glucose stimulation or treatment with 35 mM KCl
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cellular
• increased beta-cell differentiation as determined by marker expression
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