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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mir802em3Gpt
endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
MGI:6456808
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Mir802em3Gpt/Mir802em3Gpt
Tg(Ins2-cre)25Mgn/0
involves: C57BL/6JGpt * DBA MGI:6456819


Genotype
MGI:6456819
cn1
Allelic
Composition
Mir802em3Gpt/Mir802em3Gpt
Tg(Ins2-cre)25Mgn/0
Genetic
Background
involves: C57BL/6JGpt * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir802em3Gpt mutation (0 available); any Mir802 mutation (2 available)
Tg(Ins2-cre)25Mgn mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in islets from mice fed standard chow or a high-fat diet after glucose stimulation or treatment with 35 mM KCl
• mice fed a high-fat diet exhibit reduced serum insulin concentrations compared with control mice
• after glucose injection or fed a high-fat diet
• in mice challenged with IPGTT or fed a high-fat diet

endocrine/exocrine glands
• increased beta-cell differentiation as determined by marker expression
• in islets from mice fed standard chow or a high-fat diet after glucose stimulation or treatment with 35 mM KCl

cellular
• increased beta-cell differentiation as determined by marker expression





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory