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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cmtm4em1Wlh
endonuclease-mediated mutation1, WenLing Han
MGI:6457028
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cmtm4em1Wlh/Cmtm4em1Wlh involves: C57BL/6J MGI:6458554


Genotype
MGI:6458554
hm1
Allelic
Composition
Cmtm4em1Wlh/Cmtm4em1Wlh
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cmtm4em1Wlh mutation (0 available); any Cmtm4 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• increased incidence of bent midpiece
• increased incidence of backward curved heads

reproductive system
N
• normal spermatogonial, primary spermatocyte, round spermatid, elongated spermatid, and Sertoli cell morphology in seminiferous tubules
• normal testis/body weight ratio
• normal cauda epididymal sperm content
• normal serum testosterone level
• increased incidence of bent midpiece
• increased incidence of backward curved heads
• low fertilization ability of spermatozoa in vitro
• fewer pregnancies after 2 months cohabitation with WT females





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory