Phenotypes associated with this allele

• Allele Symbol: Cep55^{tm1c(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6458053
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Cep55^tm1c(EUCOMM)Hmgu/Cep55^tm1c(EUCOMM)Hmgu Gt(ROSA)26Sor^tm9(cre/ESR1)Arte/Gt(ROSA)26Sor^+	involves: C57BL/6N * C57BL/6NTac	MGI:6458519
cn2	Cep55^tm1c(EUCOMM)Hmgu/Cep55^tm1c(EUCOMM)Hmgu Tg(Vil1-cre)20Syr/0	involves: C57BL/6N * DBA/2	MGI:6458516

Genotype
MGI:6458519

cn1

• Allelic Composition: Cep55^{tm1c(EUCOMM)Hmgu}/Cep55^{tm1c(EUCOMM)Hmgu}; Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺
• Genetic Background: involves: C57BL/6N * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased cell nucleus count ( J:287102 )

• neural progenitor cells treated with tamoxifen exhibit increased binucleated and pyknotic cells compared with controls

• slightly increase in the number of binucleated mouse embryonic fibroblasts treated with tamoxifen

Genotype
MGI:6458516

cn2

• Allelic Composition: Cep55^{tm1c(EUCOMM)Hmgu}/Cep55^{tm1c(EUCOMM)Hmgu}; Tg(Vil1-cre)20Syr/0
• Genetic Background: involves: C57BL/6N * DBA/2

digestive/alimentary system

digestive/alimentary phenotype ( J:287102 )

N • cell survival in adult intestine is normal