Phenotypes associated with this allele

• Allele Symbol: Tg(Thy1/THY1)hT10Gsv
• Allele Name: transgene insertion hT10, Frank Grosveld
• Allele ID: MGI:6458481
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Thy1/THY1)hT10Gsv/0	involves: C57BL/10 * CBA	MGI:6458495

Genotype
MGI:6458495

tg1

• Allelic Composition: Tg(Thy1/THY1)hT10Gsv/0
• Genetic Background: involves: C57BL/10 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:133943 )

neoplasm

increased kidney tumor incidence ( J:133943 )

• mice develop cystic neoplasms in the kidney derived from the proximal tubules through an intermediate in situ tumor

renal/urinary system

increased kidney tumor incidence ( J:133943 )

• mice develop cystic neoplasms in the kidney derived from the proximal tubules through an intermediate in situ tumor

abnormal renal tubule epithelium morphology ( J:133943 )

• in some tubules, the epithelial cells show nuclear variability, increase in nuclear size, and a high mitotic rate, leading to closure of the tubules